Most Popular THC Seltzers in Colorado

Colorado is an early adult-use market with a mature beverage segment and several legacy local brands, making it one of the country’s most exciting states for THC-infused drinks. These seltzers offer a social, fast-acting alternative to traditional edibles, with effects that can kick in as soon as 10 minutes thanks to nano-emulsification technology. Whether you’re exploring cannabis-infused beverages for the first time or seeking new options beyond your usual dispensary picks, Colorado’s selection includes everything from Boulder’s pioneering brands to innovative newcomers. For understanding the science behind these fast-acting formulas, Herb’s educational guides explain how nano-emulsification technology creates consistent, rapid-onset experiences.

• Colorado offers a mature THC beverage market: Home to pioneering brands like Keef and innovative newcomers like Ska Brewing’s Lo Dose, the state features a broad and competitive selection of cannabis seltzers
• Purchasing channels vary by product type: Dispensary-exclusive products (marijuana-derived) follow standard edible potency limits (10mg per serving, 100mg per package). Colorado also regulates hemp-derived THC products under CDPHE rules with strict thresholds: no more than 1.75mg THC per serving and a CBD:THC ratio of at least 15:1
• Dosage variety meets every need: From microdose 1mg options for beginners to 100mg high-potency drinks for experienced users, Colorado’s selection covers the full spectrum
• Local brands dominate sales: Colorado-created brands like Keef hold top spots in statewide sales, appearing multiple times in Headset’s top 10 best-selling cannabis beverages
• Fast-acting effects define the category: Unlike traditional edibles that can take 30 minutes to 2 hours (sometimes longer), THC seltzers can deliver effects in as little as 10 minutes, often with a shorter duration than traditional edibles, though individual experiences vary by formulation, dose, and personal factors

Keef Brands is one of Colorado’s earliest cannabis beverage brands, founded in Boulder in 2010. This local heritage brand has maintained market leadership through consistent quality and innovation, with their products appearing repeatedly among Colorado’s top sellers. The Bubba Kush Root Beer has been marketed as a Cannabis Cup winner for Best Edible (2015 High Times Cannabis Cup), building a strong reputation among cannabis connoisseurs.

Keef’s success stems from their deep understanding of Colorado’s cannabis culture and their proprietary emulsification technology that ensures consistent effects across all products. Whether you’re shopping at a Denver dispensary or exploring options in mountain towns, Keef’s recognizable cans are a staple of the local cannabis scene.

What Makes Them Special:

• Market leadership: Appears multiple times in Colorado’s top 10 best-selling cannabis beverages according to Headset sales data
• Comprehensive product range: Offers everything from 10mg sodas to 100mg high-potency options, plus zero-calorie Slims with balanced THC:CBD ratios
• Colorado heritage: As one of the earliest cannabis beverage companies in the state, they’ve built deep relationships with local dispensaries and consumers
• Award-winning flavors: The Bubba Kush Root Beer remains a cult favorite, while newer options like Blue Razz and Purple Passion appeal to diverse palates

Best For: Cannabis enthusiasts seeking reliable, consistent effects; Colorado locals who want to support homegrown brands; shoppers looking for the widest variety of potency options

Where to Buy in Colorado: Available at many dispensaries across Colorado; availability varies by retailer and location

Weller represents Boulder’s continued innovation in the cannabis beverage space, offering balanced 5mg THC + CBD (5mg each) sparkling waters alongside their THC-free CBD line. Founded in Colorado, Weller has cultivated a loyal following among locals who appreciate their straightforward approach to microdosing and their role in the state’s evolving cannabis culture.

The brand’s appeal lies in its simplicity and local roots. Weller was created for Colorado’s unique cannabis market, understanding local preferences for balanced, social doses that complement the state’s active lifestyle.

What Makes Them Special:

• Colorado roots: A locally-founded brand that understands Colorado’s cannabis culture and consumer preferences
• Balanced dosing: The 5mg THC + 5mg CBD per can provides a gentle, manageable experience perfect for newcomers to cannabis beverages
• Dual product lines: Offers both THC-infused and THC-free CBD options, allowing consumers to choose based on their desired experience
• Thoughtful formulation: Focuses on clean ingredients and straightforward effects rather than complex flavor profiles

Best For: Cannabis beverage newcomers; Colorado locals seeking hometown brands; consumers who prefer simple, consistent microdosing experiences

Where to Buy in Colorado: Available at select Colorado dispensaries; check retailer availability in your area

Ska Brewing brings over 30 years of Colorado craft brewing expertise (founded in 1995) to the cannabis beverage market with their 2026 launch of Lo Dose THC seltzers. Based in Durango, this established brewery applied their beverage craftsmanship to create a hemp-derived, non-alcoholic 1.5mg THC + 25mg CBD formula designed specifically for social occasions. As co-founder Dave Thibodeau explains, “This new option isn’t a reaction; it’s a continuation of what we already believe in. It’s about staying present, staying social, and keeping things feeling right.”

The brewery’s transition into cannabis beverages represents a significant trend in Colorado’s market, where established beverage companies are leveraging their expertise to create sophisticated, low-dose options. Notably, Ska’s Lo Dose formula (1.5mg THC with a roughly 17:1 CBD:THC ratio) aligns with Colorado’s hemp product thresholds, making it one of the few THC beverages that may qualify for sale outside the dispensary system.

What Makes Them Special:

• Craft brewery pedigree: Over 30 years of beverage expertise applied to cannabis formulation
• Ultra-low THC: At 1.5mg THC, it’s one of the gentlest options available, ideal for microdosing
• High CBD content: The 25mg CBD creates a balanced, anxiety-free experience
• Colorado authenticity: As a long-standing Colorado brewery, they bring genuine local credibility to the cannabis space

Best For: Dry January participants; microdosing enthusiasts; craft beverage lovers exploring cannabis alternatives

Where to Buy in Colorado: Available at Ska’s World Headquarters in Durango and at other Colorado retailers; sales channel varies by location

Cycling Frog earned the title of Top Overall THC Drink by Leafly in 2026, a testament to their exceptional quality and thoughtful formulation. Based in the Pacific Northwest, their hemp-derived seltzers have gained national popularity for their sustainable sourcing and impeccable flavor profiles. The brand’s commitment to quality extends from their no-spray Oregon farm through their entire seed-to-sip process, resulting in products that have been featured in major publications including Bon Appétit.

What sets Cycling Frog apart is their attention to detail at every level, from their aesthetically pleasing branding to their carefully balanced cannabinoid ratios. Their 5mg THC + 10mg CBD formula provides a social, uplifting experience without anxiety, while their potency range (from 2mg up to 50mg across product formats) accommodates everyone from microdosing beginners to high-tolerance enthusiasts.

Important Colorado note: Cycling Frog’s standard 5mg THC + 10mg CBD products (a 2:1 CBD:THC ratio) do not meet Colorado’s hemp product thresholds of 1.75mg THC per serving and a 15:1 CBD:THC ratio. Colorado availability may be limited or may require purchase through different channels. Consumers should confirm product compliance and availability at point of sale.

What Makes Them Special:

• Industry recognition: Rated #1 overall THC drink by Leafly for their impeccable flavor and potency options
• Sustainable sourcing: Hemp grown on their own no-spray farm in central Oregon ensures quality control from seed to sip
• Wide potency range: Offers options from 2mg to 50mg across their product line
• Award-winning design: Praised for aesthetically on-point branding that appeals to design-conscious consumers

Best For: Quality-focused consumers; those seeking sustainable, thoughtfully-produced products; shoppers wanting a range of potency options

Where to Buy in Colorado: Check the brand’s website for Colorado-specific availability; confirm compliance at point of sale

Crescent 9 is a nationally prominent THC drink brand. According to a Business Wire release, the company states that Nielsen rated Crescent 9 as the #1-selling THC drink in stores nationwide. Their success stems from offering a wide potency range (5mg, 10mg, 20mg, and 50mg THC) in a single product line, allowing consumers to customize their experience based on their tolerance and desired effects. Made with real fruit purées and juices, Crescent 9 delivers authentic flavor profiles that have earned them recognition as the Best High-Potency THC Drink by Leafly in 2026.

The brand’s appeal lies in their combination of quality, variety, and accessibility. Their extensive potency options ensure there’s something for everyone from cautious beginners to experienced cannabis users.

Important Colorado note: Hemp-derived products at 5mg THC or higher do not meet Colorado’s hemp thresholds. Colorado availability and purchase channels may differ from other states. Confirm product compliance at point of sale.

What Makes Them Special:

• National sales prominence: Crescent Canna reports a Nielsen #1 ranking for in-store THC drink sales
• Unmatched potency range: Offers 5mg, 10mg, 20mg, and 50mg options in the same product line
• Authentic ingredients: Made with real strawberry purée and fruit juices rather than artificial flavors
• Comprehensive lab testing: Full-panel testing with results available online ensures product safety and consistency

Best For: Consumers seeking variety in potency; those wanting nationally-recognized quality

Where to Buy in Colorado: Check local retailers for availability; confirm product compliance at point of sale

Cornbread Hemp earned strong recognition at the 2025 High Spirits Awards, taking home 2 Gold medals (Blueberry and Salted Watermelon) and 1 Silver medal (Raspberry Limeade) for their Kentucky-crafted THC seltzers. The Salted Watermelon variety received particular praise for its sophisticated salt balance that elevates a familiar flavor profile, while their pure THC formulation (without CBD) delivers clear, social, and uplifting effects perfect for gatherings. As a Leafly Best THC Seltzer winner in 2026, Cornbread has established itself as a premium option for consumers seeking award-winning quality.

What distinguishes Cornbread from competitors is their commitment to pure THC experiences without CBD dilution, appealing to consumers who want straightforward psychoactive effects. Their 5mg dosage provides a consistent, manageable experience, while their low calorie count (30 per can) caters to health-conscious consumers.

Important Colorado note: As with other hemp-derived 5mg THC products, Cornbread’s seltzers may not meet Colorado’s hemp thresholds. Confirm compliance and availability at point of sale.

What Makes Them Special:

• Award recognition: 2025 High Spirits Awards medals across multiple categories
• Pure THC formulation: No CBD means clearer, more predictable psychoactive effects
• Natural ingredients: Real fruit flavors with a low calorie count
• Kentucky craftsmanship: Small-batch production with attention to quality details

Best For: Social cannabis users; award-winning quality seekers; those preferring pure THC experiences without CBD

Where to Buy in Colorado: Check the brand’s website for Colorado-specific availability; confirm compliance at point of sale

Wynk has carved out a unique niche as the Best Zero-Calorie THC Drink according to Leafly’s 2026 rankings, appealing to health-conscious consumers who don’t want to compromise on flavor or effects. Their 0-calorie, 0-sugar formulation delivers a clean, guilt-free cannabis experience with balanced 1:1 THC:CBD ratios that provide gentle, social effects without anxiety. The brand reports fast onset times and availability in bars across multiple states, making Wynk a favorite among fitness enthusiasts and calorie-conscious cannabis users.

The brand’s success demonstrates the growing demand for health-focused cannabis products that align with active lifestyles. Unlike sugary sodas or high-calorie alternatives, Wynk’s zero-everything approach allows consumers to enjoy cannabis beverages without worrying about sugar intake or empty calories, making it particularly popular among health-conscious demographics.

What Makes Them Special:

• Zero everything: 0 calories and 0 sugar per the brand’s marketing
• Balanced cannabinoid ratio: 1:1 THC:CBD provides gentle, manageable effects
• Multiple dosage tiers: Available in 2.5mg, 5mg, and 10mg options to suit different tolerance levels
• Bar availability: One of the few THC beverages reported to be available in bars, expanding consumption options beyond home use

Best For: Health-conscious consumers; fitness enthusiasts; those seeking zero-calorie cannabis options

Where to Buy in Colorado: Wynk does not ship direct-to-consumer to Colorado; check local retailers for in-store availability

Cann Lo Boys has gained recognition for being available at select Colorado retailers, positioning it as a THC seltzer that can be enjoyed in social settings. Their ultra-low 1mg THC + 15mg CBD formulation creates a gentle, mind-opening buzz perfect for beginners or those seeking subtle effects. Described by Bon Appétit as a standout in the social cannabis space, Cann’s approachable dosing and sophisticated botanical flavors (like Grapefruit-Rosemary and Lemon-Lavender) have made them a favorite among cannabis newcomers.

Cann’s retail presence represents a significant shift in cannabis consumption culture, normalizing THC beverages as social alternatives to alcohol. With just five simple ingredients (cannabis extract, sparkling water, organic agave, fruit juices, and botanicals), Cann delivers clean, sophisticated flavors that appeal to discerning palates without overwhelming THC effects. Notably, with 1mg THC and 15mg CBD (a 15:1 CBD:THC ratio), Cann Lo Boys fall within Colorado’s hemp product thresholds.

What Makes Them Special:

• Retail availability: Available at select Colorado retailers; on-premise availability varies
• Ultra-low dosing: 1mg THC is perfect for true microdosing and first-time users
• Sophisticated flavors: Botanical infusions create unique, adult-oriented taste profiles
• Simple ingredients: Just five clean ingredients ensure quality and consistency

Best For: First-time cannabis users; social drinkers seeking alcohol alternatives; Dry January participants

Where to Buy in Colorado: Available at select Colorado retailers; on-premise availability varies by location

BRĒZ revolutionizes the THC seltzer category by combining cannabinoids with functional mushrooms, creating targeted effects that go beyond standard cannabis experiences. Their OG Social Tonic features 5mg THC + 10mg CBD + 2200mg Lion’s Mane mushroom, designed to deliver clear-headed euphoria that enhances social interactions without anxiety. Recognized as having the Best Unique Buzz by Leafly in 2026, BRĒZ offers different formulations for specific needs: OG for socializing, Amplify for energy, and Drift for relaxation.

The brand’s innovation lies in their understanding that modern consumers want more than just THC: they want functional benefits that enhance their lifestyle. By combining cannabinoids with adaptogens and nootropics, BRĒZ creates multi-dimensional experiences that address specific needs while maintaining the fast-acting benefits of nano-emulsified THC.

What Makes Them Special:

• Functional mushroom blends: Lion’s Mane, Cordyceps, and other mushrooms add cognitive and wellness benefits
• Targeted effect profiles: Different formulations for social, energy, and relaxation needs
• Clear-headed effects: Balanced cannabinoid ratios prevent anxiety while enhancing social experiences
• Major retail distribution: Reported to be available in over 2,000 stores including Total Wine, Wegmans, and Sprouts (note: retail distribution may include THC-free SKUs; THC product availability varies by state)

Important Colorado note: BRĒZ’s standard 5mg THC + 10mg CBD products do not meet Colorado’s hemp thresholds. Confirm product compliance and availability at point of sale.

Best For: Consumers seeking functional benefits; social cannabis users; those wanting enhanced cognitive effects

Where to Buy in Colorado: Check the brand’s website and local retailers for Colorado-specific availability; confirm compliance at point of sale