Dispensaries in Guadalupe

Guadalupe occupies a unique position in Arizona’s thriving cannabis landscape as home to one of the state’s most innovative dispensaries. Since Arizona voters legalized recreational cannabis through Proposition 207 in 2020, this small town just south of Tempe has become a destination for both medical patients and adult-use consumers. With both medical marijuana legal since 2010 and recreational cannabis widely accessible, Guadalupe offers convenient access to premium products with some of the most progressive operating hours in the state. The community’s cannabis-friendly approach has attracted major operators while maintaining its close-knit, welcoming atmosphere that extends to its dispensaries.

1. The Mint Cannabis – Tempe

Located on South Priest Drive just across from Tempe’s Arizona Mills Mall, The Mint Cannabis operates Arizona’s largest licensed cannabis dispensary at over 12,000 square feet. This flagship location made history in 2022 as the first dispensary in Arizona to offer 24-hour service on weekends, providing unprecedented accessibility for consumers with varied schedules. The facility houses an indoor cultivation center, an innovative cannabis kitchen serving infused foods, and a convenient drive-thru for expedited service. Medical patients and recreational customers alike appreciate the pharmacy-style approach combined with cutting-edge convenience features that make The Mint a standout destination.

Key Features:

• 24-hour operation Friday through Sunday, extended weekday hours Monday through Thursday
• Drive-thru service for quick pickup without leaving your vehicle
• On-site cannabis kitchen serving THC-infused meals and snacks
• Online ordering with curbside pickup and delivery options
• Medical patient discount programs including veterans, seniors, and distinguished citizens
• Massive 12,000 square foot facility with spacious shopping areas

Product Highlights: The Mint maintains one of Arizona’s most extensive cannabis inventories with over 400 different products from top state cultivators. Their selection includes premium private reserve flower hand-selected from Arizona’s best growers, World THC Factory concentrates that consistently sell out, and a comprehensive range of edibles, topicals, tinctures, and cartridges. The Connected Cannabis Co. products and daily rotating specials on flower and concentrates provide options across all price points while maintaining quality standards.

2. Trulieve Guadalupe

Conveniently positioned in Guadalupe with easy access for residents throughout the southeast Valley, Trulieve brings its national expertise to the local community with a focus on hand-grown, premium cannabis. Part of a network of over 180 dispensaries nationwide, this location combines the resources of a major operator with personalized service from experienced staff who prioritize education and patient care. The dispensary serves both medical marijuana patients with qualifying conditions and recreational customers over 21, offering a controlled-environment approach that minimizes chemicals and maintains natural growing processes from seed to sale.

Key Features:

• Part of Trulieve’s nationwide network with consistent quality across locations
• First-time customer discounts up to 25% off entire purchase
• Online ordering for same-day pickup with streamlined in-store process
• Hand-grown cannabis in controlled environments designed to reduce pesticides
• Knowledgeable cannabists trained in product effects and medical applications
• Strategic location with access to multiple nearby Trulieve locations in Tempe and Chandler

Product Highlights: Trulieve stocks a carefully curated selection spanning multiple cannabis categories with an emphasis on their proprietary cultivated flower. The inventory includes diverse strain options across indica, sativa, and hybrid varieties, alongside concentrates, vape cartridges, and edibles. Their vertical integration allows for competitive pricing on house brands while also carrying trusted third-party products to give customers comprehensive choices for both recreational and therapeutic needs.

3. Sticky Saguaro

Situated in nearby Chandler on East Riggs Road, Sticky Saguaro has built a loyal following since 2017 as a family-owned dispensary prioritizing quality, customer service, and community connection. The welcoming atmosphere starts at the door with friendly reception staff and continues through their knowledgeable budtenders who take time to educate customers regardless of experience level. Operating daily from 9am to 9pm including holidays, this locally-owned shop offers both walk-in service and online pre-ordering with express pickup windows. Medical marijuana patients and recreational customers find a comfortable shopping environment that balances professionalism with approachability.

Key Features:

• Family-owned and locally operated with deep community roots
• Express walk-up windows for pre-order pickup without waiting
• Open 365 days per year including all holidays
• Loyalty points program with rewards on every purchase
• Daily deals with tax-included pricing for transparent shopping
• Veteran, senior, and patient assistance discount programs

Product Highlights: Sticky Saguaro maintains relationships with Arizona’s premier cultivators to ensure high-quality flower selection with 30-plus rotating strains. Customer favorites include their fresh flower that reviewers consistently praise for potency and aroma, popular edible brands including gummies at competitive dosages, and a solid concentrate selection featuring cartridges and live resin. The dispensary’s commitment to product testing and vendor lab verification provides confidence for medical patients seeking consistent, reliable products.

4. Ponderosa Dispensary – Tempe/Mesa

Operating since 2013, Ponderosa Dispensary brings over a decade of cannabis expertise to the greater Guadalupe area with locations throughout the Valley. After joining forces with premium cultivator Sonoran Roots in 2021, Ponderosa solidified its reputation for top-tier products and unmatched customer service that regulars affectionately call “Pondy.” The Tempe/Mesa location serves the communities surrounding Guadalupe with a focus on quality-first philosophy and in-house brands Sonoran Roots flower and Canamo Concentrates that showcase Arizona’s craft cannabis scene. This locally-owned operation maintains the personal touch of an independent shop backed by sophisticated cultivation and extraction capabilities.

Key Features:

• Over 11 years serving Arizona’s cannabis community with established reputation
• Vertically integrated with Sonoran Roots cultivation and Canamo extraction lab
• Extended hours 9am to 9pm daily for convenient access
• Online ordering through multiple platforms for pickup
• Loyalty rewards and weekly specials across product categories
• Multiple Valley locations providing consistent experience

Product Highlights: Ponderosa specializes in Sonoran Roots premium flower known for patient drying, proper curing, and hand-trimming that prioritizes quality over speed. Their top-tier flower selection features craft cannabis grown in-house alongside carefully selected third-party cultivators. The concentrate section highlights Canamo products widely regarded as some of Arizona’s best extracts, created from the finest input material. Edibles, vapes, and topicals round out an inventory designed for both medical patients seeking therapeutic benefits and recreational consumers exploring Arizona’s cannabis culture.

5. Curaleaf – 48th Street

Located just north of Guadalupe on 48th Street near Tempe, Curaleaf operates a spacious, modern dispensary that brings national brand consistency with local community feel. This Phoenix location stands out among Curaleaf’s 12 Arizona dispensaries for its fresh inventory, expansive selection, and friendly budtender staff who provide educational support for customers navigating cannabis options. The dispensary accepts debit card payments—a rarity in Arizona’s largely cash-based cannabis market—making transactions more convenient for customers. Medical marijuana patients benefit from free delivery service while recreational customers enjoy daily deals and a diverse product lineup.

Key Features:

• Debit card payment accepted, eliminating ATM fees common at other dispensaries
• Free delivery service for medical marijuana patients throughout the area
• Daily specials rotating across vape cartridges, edibles, flower, and concentrates
• First-time customer and veteran discount programs
• Online pre-ordering for expedited in-store pickup
• Clean, inviting retail space with extensive product displays

Product Highlights: Curaleaf offers a vast selection including their house-brand FIND everyday flower at accessible price points, Select vape cartridges known for quality and consistency, and comprehensive CBD and THC product ranges. The inventory spans flower in multiple strain varieties, pre-rolls for convenience, tinctures, gummies, concentrates, capsules, and edibles produced to rigorous testing standards. Their national scale ensures product consistency while local sourcing brings Arizona-grown options that support the state’s cannabis cultivation community.